10 June 2008
For the right price, a California company will clone your canine companion

Remember Snuppy, the first dog ever cloned in 2005? Well, he now has three collielike comrades, recently cloned from Missy, a pet who died in 2002. And more may be on the way: BioArts International in Mill Valley, California, a start-up catering to offbeat biotech needs, announced this week that it's holding an auction to see how much five members of the public will pay to have their pooches cloned. BioArts CEO Lou Hawthorne says his company is collaborating with the crack dog-cloning team headed by disgraced South Korean scientist Hwang Woo-Suk, who is now chief scientist at the 2-year-old Suam Bioengineering Research Institute outside of Seoul. Hawthorne tried for years to clone his beloved dog Missy, first with the "Missyplicity" project at Texas A&M University and then with his now-defunct company Genetic Savings and Clone. He finally got his wish from Hwang's team in Korea, and he's now ready to share his good luck with the world in a "Best Friends Again" program. It entails five auctions, with starting bids ranging from $100,000 to $180,000. Hawthorne says a half-dozen would-be clients registered in the first 48 hours for the 18 June auctions. BioArts this month got a worldwide license giving it exclusive rights to perform commercial dog and cat cloning with the somatic cell nuclear transfer technique developed for Dolly, Hawthorne says.

Some scientists, including Rudolf Jaenisch of the Massachusetts Institute of Technology in Cambridge, have warned that virtually all clones have something wrong with them, and like Dolly, the first cloned sheep, are likely to develop multiple health problems and die prematurely. The Humane Society of the United States and the American Anti-Vivisection Society blasted BioArts in a press release, calling pet cloning "a bizarre scientific endeavor fraught with failures and animal suffering." But Hawthorne is unfazed. "Some clones are perfect, some are not," he says. He claims his Missy clones, now 3 and 6 months old, are "perfectly healthy" and that CC, the first cat clone produced at Texas A&M in 2001, is a mother now and still going strong. Hawthorne also says the Koreans have dramatically improved the success rate post-Snuppy, in large part with technology enabling them to pinpoint exactly when tricky canine ova are ready for fertilization. As a result, he says, the team is now able to get viable embryos with almost all the eggs it injects with nuclear material from a dog's skin cells. And, he says, they have gotten births from 25% of the embryos inserted in females.

ScienceNow
June 10, 2008

Original web page at ScienceNow